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Schenectady County Community College

Nocardia spp.


Gram stain:  positive
Cell shape:  rods; club-shaped and pleomorphic
Arrangement:  
Oxygen requirements:  
Other:  Form rudimentary filaments that break into short rods; acid fast organism.

Habitat:  common in soil; widespread throughout nature.

Pathogenicity:  occasionally cause chronic, difficult to treat pulmonary nocardiosis that can be lethal in immunosuppressed patients. May also cause mycetoma - a localized destructive infection of the feet or hands causing chronic, draining abscesses of the tissues and bones.

Treatment:  

*Can cause problems in wastewater plants - causes "bulking" of the fecal material and causes operational problems; potentially dangerous to workers. Nocardia orientalis produces the antibiotic vancomycin.


LINKS

Bug Bytes - Nocardiosis
Pediatric Online - Nocardia
Vancomycin
Vancomycin - Usage and Monitoring Guidelines
Wastewater Organisms Database